To confirm increased CD68 in skeletal muscle on the protein level, we stained for CD68 in a subset of patients with sufficient quality of histological slides (n = 13, n = 19 and n = 11 patients in control, IR and sepsis groups, respectively) and found significantly increased CD68 staining in patients with sepsis compared to control and IR (p < 0.05, Fig. 1c). The gene discussed is CD68; the disease is Sepsis.