We also concluded that patients with LN max ≥ 4.03 showed unfavorable OS compared those with LN max < 4.03 among patients with WHO grade II-IV IDH mutant astrocytoma, although no significant difference in OS was evident between IDH wild-type WHO grade II-IV astrocytoma with LN max ≥ 4.03 and those with LN max < 4.03. The gene discussed is IDH1; the disease is astrocytoma (excluding glioblastoma).