We find that the negative associations between GATA4 loss and immune infiltration are significant in 5 out of 8 tissue types when normalizing all other correlated and anticorrelated copy number events: breast invasive carcinoma, head and neck squamous cell carcinoma, lung squamous cell carcinoma, lung adenocarcinoma, and uterine corpus endometrial carcinoma (Fig. 3e). Here, GATA4 is linked to head and neck squamous cell carcinoma.