Additionally, we assessed TMPRSS2 expression in multiple cancer cell lines based on the CCLE database and found that TMPRSS2 expression was high in COAD, BRCA, PAAD, STAD and PRAD cells but low in AML, MESO, ALL and LUSC cells (Supplementary Figure 1C). The gene discussed is TMPRSS2; the disease is acute myeloid leukemia.