Kang et al. recently identified 15 DEGs from skeletal muscle of sarcopenia patients [26] and, surprisingly, the majority (10/15) of them corresponded with our mouse DEGs (28m vs. 24m; Padj <0.05): five DEGs overrepresented (Runx1, Bcl3, Acsl5, Ngfr, and Chi3l1) and five underrepresented (Ndufb5, Tcap, Slc253a, Cyc1, and Acat1) in old-old samples. Here, CYC1 is linked to sarcopenia.