SLAMF6 and rheumatoid arthritis: Since the frequency of genotype CC was remarkably higher in patients than in normal controls, it was plausible that the mutant allele C added to the risk of RA via regulation of SLAMF6. Interestingly, as shown in HaploReg database [23], rs148363003 is predicted to alter transcription factor-binding sites of SLAMF6. A fine-mapping of the genomic region around rs148363003 is warranted to further elucidate its regulatory role in the tissue expression of SLAMF6.