In 2009, Sathish et al. [39] found that incubation of human ASM cells with IL-13 reduced the expression of SERCA2b, but in our study, we did not observe changes in the percentage of ASM cells that expressed IL-13 in the asthma model or the relationship of IL-13 expression with pathophysiological changes, although an association between IL-13 and SERCA2b in ASM cells was observed. This evidence concerns the gene IL13 and asthma.