They also identified several T2DM-associated CpG sites (cg1231141 (ADAMTS2), cg19534769 (HGFAC), and cg13163919 (TLE3) implicated in inflammation, pancreatic β-cell function, and T2DM pathogenesis [36] in PWH for further investigation. Here, HGFAC is linked to type 2 diabetes mellitus.