However, a significant increase in the percentage of CGRP-positive neurons that coexpress GABA (34.0% ± 3.9% in MI vs. 20.2% ± 3.1% in normal, P = 0.02) and GAD2 was observed (41.6% ± 3.4% in MI vs. 31.6% ± 2.3% in normal, P = 0.04) after MI. The gene discussed is GAD2; the disease is myocardial infarction.