ADIPOR1 and Parkinson disease: For instance, the ceramide C24:1 (d18:1/24:1), which we found as one of the top elevated ceramides in the retina and RPE of AdipoR1–/– mice, was also identified as one of the 2 (next to d18:0/24:1) most highly elevated lipids in the primary visual cortex of Parkinson’s disease patients (50).