For instance, mice with Asah1 deficiency also exhibited retinal pathology and impaired visual function, although the changes in retina structure were vastly different from those observed with AdipoR1–/– mice, with no photoreceptor degeneration in ~9-week-old mice but with severe retinal dysplasia and increased thickness of the ONL in those same mice (52). Here, ASAH1 is linked to Retinal dysplasia.