The two most downregulated genes in both groups (0–80T, 0–140T) were POSTN (periostin osteoblast specific factor) and ovin ZFNLOC101104520 (zinc finger protein) (Supplementary Table 2: day 80 and day 140 testes, respectively: POSTN: −1.4- and −2.0-fold change, associated with tumour progression and LOC101104520: −1.3- and −1.2-fold change, respectively). Here, ZNF146 is linked to neoplasm.