The results illustrated that, following DDP treatment, silencing XIAP reversed the improvement in IC50 values of NSCLC cells by CAFs-oe-EVs (p < 0.05, Figure 6b), in addition to countering the effects of CAFs-oe-EVs on the promotion of proliferation ability and inhibition of apoptosis of NSCLC cells (p < 0.05, Figure 6c-d). Here, XIAP is linked to non-small cell lung carcinoma.