XIAP and non-small cell lung carcinoma: In the current study, we sought to investigate the role of CAFs-EVs in DDP resistance in NSCLC cells, and uncovered that lncRNA SNHG12 carried by CAFs-EVs could stabilize RNA stability and transcription of XIAP by binding to HuR, and further augment the proliferation and limit the apoptosis of NSCLC cells, and finally promote DDP resistance in NSCLC cells.