ERBB2 and breast cancer: In this study, we demonstrate the developmentof clinically relevantantibody-functionalized carnauba wax nanoparticles to target humanepidermal growth factor receptor 2 (HER2)-positive breast cancer cells.The previously described preadsorption methodology27 is applied for antibody decoration of carnauba wax nanoparticles,which provides a feasible and effective functionalization process.In this way, complexity in surface modification of nontoxic and chemicallyinert carnauba wax21 nanoparticles canbe overcome.