For patients without Lynch syndrome, APC was identified as the gene associated with the most mutations (n = 14) and was followed by BRCA1 (n = 8), RAD50 (n = 7), MUTYH (n = 5), ATM (n = 5), and BRCA2 (n = 4) (Figure 1B, right panel). Here, BRCA1 is linked to Lynch syndrome.