SEC61A1 and cancer: Sec61α is a mycolactone‐sensitive Sec61 client that was mildly upregulated by mycolactone in previous proteomic studies using various cancer cell lines (Grotzke et al, 2017; Morel et al, 2018), suggesting that UPR‐mediated increase in Sec61α gene expression may override Sec61 blockade, at least to a limited extent.