This is supported by studies screening SARS-CoV-2 epitopes in COVID-19 and uninfected patients which have observed SARS-CoV-2 epitopes specific CD4+ and CD8+ T cell responses in SARS-CoV-2 uninfected individuals, which share homology with epitopes in other human coronaviruses [6, 8–10, 31]. This evidence concerns the gene CD8A and COVID-19.