Consistent with the dissociated expression between the mRNA and protein of YAP1‐1 and YAP‐2 isoforms in pancreatic cancer cells, we observed lower expression of YAP1‐2 protein in NSCLC, despite its higher expression at mRNA level compared to YAP1‐1. This evidence concerns the gene YAP1 and familial pancreatic carcinoma.