PTPRC and Sepsis: In keeping with a sepsis-associated immune depletion that also impacted other organs and tissues, flow cytometric analysis of cell suspensions from lungs and spleens of the same animals at 48 h post-CLP also demonstrated reduced total numbers of CD45+ cells and of some lymphoid and myeloid subpopulations, that was less marked in the double-dose treated group (Supplementary Figs. S3 and S4).