In another study on kidney tissue (tubules) from patients with DKD, CpG methylation in ANKRD11 as well as ARID3A, SKI, BCL11B, MRFAP, ETS11 and KCNQ1 loci were correlated with gene expression levels, supporting a functional role of DNA methylation22. The gene discussed is KCNQ1; the disease is diabetic kidney disease.