Similarly, out of 14 genes involved in DNA mismatch repair, 10 (i.e., RFC5, RFC4, RFC3, RFC1, PCNA, MSH6, MSH3, MSH2, LIG1, and EXO1) show significantly higher expression levels in OS tumor samples than normal controls (see Supplementary Fig. S1e). The gene discussed is RFC1; the disease is neoplasm.