Out of 11 genes associated with the non-homologous end joining, 4 (i.e., XRCC4, PRKDC, FEN1, and DCLRE1C) display significantly higher expressions in OS tumor samples than normal controls while DNTT has no detectable expression in normal controls (see Supplementary Fig. S1d). The gene discussed is XRCC4; the disease is neoplasm.