Cases harboring concordant sequences of KRAS and GNAS mutations between malignant-potential IPMN and A-IPMN dissected regions were more frequent among BD-IPMN cases than among MD-IPMN and mixed IPMN cases (80% vs. 12%, p = 0.0319). The gene discussed is GNAS; the disease is pancreatic intraductal papillary-mucinous neoplasm.