Specifically, we applied a mRNA panel consisting of KI67 (indicative of cell proliferation), POLR2A, BRCA1, MTOR, NCOA2, and NCOA3 to highly scattering and autofluorescent human melanoma skin biopsy FFPE tissues obtained from and characterized by the UCI Dermatopathology Center. Here, POLR2A is linked to melanoma.