Because ADNP, which contains 9 zinc fingers and a homeodomain, showed the highest peptide abundance across three replicates (Supplementary Fig. 3e), is enriched in RHΔ-Turbo compared to Turbo alone (Supplementary Fig. 3f), and is relevant to autism spectrum disorders, we chose to further examine its function at R-loops. This evidence concerns the gene ADNP and autism spectrum disorder.