We performed enrichment analysis of Tau and Aß-induced changes in astrocytes for AD risk genes and sub-threshold risk loci21, using an approach recently performed on microglia22, focussing on the 9938 genes expressed > 1FPKM in our TRAP-seq data for which a gene-level GWAS p value was available21, looking for enrichment in genes induced >1.5-fold (p_adj<0.05) within our data sets. Here, MAPT is linked to Alzheimer disease.