YUMM1.7 tumors from GPR182−/− mice demonstrated significantly increased CD45+ immune cells and CD3+ T cells both in proportions and in densities (Fig. 3a, b, and Supplementary Fig. 3a); except for the small group of polymorphonuclear myeloid-derived suppressor cells (PMN-MDSC) (Supplementary Fig. 3b), we did not observe any significant difference in non-T cell populations, including natural killer (NK) cells, tumor-associated macrophages (TAMs), DCs or total MDSC (Fig. 3b). Here, PTPRC is linked to neoplasm.