ACKR5 and neoplasm: To investigate if GPR182 affects tumor growth, we obtained the Gpr182tm2q(KOMP)Wtsi/+ (GPR182lacZ/+) mouse (hereafter referred to as the GPR182+/− mouse) from the Knockout Mouse Project (KOMP) repository and backcrossed to achieve homozygous GPR182lacZ/lacZ (hereafter referred to as GPR182−/−) mice as described by Kechele et al.22.