This revealed enrichments of association signal within the set of 24 MM lead variants for all three Ig isotypes (binomial test P = 6.8 × 10−5 for IgA, P = 0.02 for IgG, P = 0.004 for IgM for the enrichment of association P values <0.05), as well as individually significant associations (Supplementary Fig. 3), including for the SMARCD3, WAC, and ELL2 associations, which also showed plasma cell cis-eQTLs (Supplementary Table 2). The gene discussed is WAC; the disease is Miyoshi myopathy.