The results of flow cytometry (Figs. 2N and S2B) and western blot analysis (Figs. 2O and S3A) showed that overexpression of CENPA inhibited the apoptosis of cells, whereas NRMT silencing counteracted the effect of CENPA on the apoptosis of retinoblastoma cells. The gene discussed is NTMT1; the disease is retinoblastoma.