While serotonergic drugs have traditionally been used in affective disorders (e.g., selective serotonin reuptake inhibitors targeting the serotonin transporter) and dopaminergic drugs are used in schizophrenia (dopamine receptor antagonists) and ADHD (targeting the dopamine transporter), such distinction becomes more and more blurred. The gene discussed is SLC6A3; the disease is schizophrenia.