In addition, the western blot assay confirmed that the expression levels of ATF4 and CEMIP in typical PCa cells (LNCaP, 22RV1, PC-3, and DU145) were significantly upregulated compared with prostate epithelial cells (RWPE-1), especially in the PC-3 and DU145 (Fig. S8B). The gene discussed is ATF4; the disease is posterior cortical atrophy.