Furthermore, the results of Western blot analysis demonstrated that EV marker proteins (CD63, Tumor Susceptibility Gene 101 [TSG101], and CD9) were present in EVs produced by NPC cells, whereas endoplasmic reticulum derived protein Calnexin was absent (Fig. 3C), and was not affected by X-IR. The gene discussed is CD63; the disease is nasopharyngeal carcinoma.