RBPJ and hepatocellular carcinoma: To verify the effect of Mφ-Exo-hsa_circ_0004658 on the regulation of HCC growth in vivo, SMMC-7721 cells transfected with sh-circRNA or sh-control or cocultured with WT Mφ-Exo, RBPJ+/+ Mφ-Exo or RBPJ+/+ Mφ-Exo-sh-circRNA were subcutaneously injected into nude mice.