In addition, among 103 ARGs, 13 ARGs have at least 5 types of AD-related evidence, including 8 well-known AD genes: APOE, PTK2B, NOS1, MEF2C, SORL1, EPHA5, ADAM10, and CD33. For the rest of the ARGs, all but BRSK1 had corresponding published literature-derived evidence. The gene discussed is BRSK1; the disease is Alzheimer disease.