As a result, SC abdominal adipose of PCOS women shows diminished insulin-mediated glucose uptake, reduced glucose transporter type 4 (GLUT-4) expression [41] and catecholamine lipolytic resistance from diminished protein levels of β2-adrenergic receptor, HSL and protein kinase A regulatory-IIβ component (PKA-RegIIβ) [42, 43]. This evidence concerns the gene INS and polycystic ovary syndrome.