Other edaravone-regulated genes with potential ALS association are also of interest, such as enzymes clearing superoxide radicals (e.g. CAT and GPX7), glutamate receptors (e.g. GRIA1, GRID2 and GRIK4) and pro-apoptotic proteins (e.g. BAX). This evidence concerns the gene GRIA1 and amyotrophic lateral sclerosis.