To validate the ability of miR-7-5p to inhibit the cellularproliferative activity of AML by targeting OSBPL11through the PI3K/AKT/mTOR signaling pathway, we transfected HL-60 and MOLM13 cellswith OSBPL11 vector and evaluated its effects onproliferation and apoptosis. Here, AKT1 is linked to acute myeloid leukemia.