Higher pre-diagnostic concentrations of interleukin 1 alpha (IL-1a), IL-8 and tumour necrosis factor alpha (TNF-A) have been associated with higher risk of ovarian cancer, whereas concentrations of serum amyloid A, soluble tumour necrosis factor receptor-2 (sTNF-RII) and monokine induced by gamma interferon (MIG) have been positively associated with lung cancer risk [10, 11]. The gene discussed is IFNG; the disease is lung carcinoma.