For instance, Fan et al. [26] demonstrated that cancer-related fibroblasts-secreted exosomal Lnc-NEAT1 promoted endometrial cancer development through upregulating miR-26a/b-5p-targeted STAT3 signaling pathway, and Shen et al. [27] testified that lncRNA NEAT1 stimulated malignant behaviors of colorectal cancer through mediating KDM5A/Cul4A and Wnt pathways. This evidence concerns the gene CUL4A and colorectal cancer.