CFTR and cystic fibrosis: However,challenges remain in choosing the best devices, both for physical activity and bodycomposition, as a consequence of rapid development of devices and absence ordeveloping cut-off points and reference values specifically for the CF population.Our sample included a small sample of patients with CFTR modulating therapies whichmakes it difficult to draw definitive conclusions on their association with CRF.However, this smaller sample corresponds to trends in CF management during our studyperiod.