In vivo treatments of BALB/c mice-bearing 4T1-breast tumor evidenced antitumor activity in all nanoformulations particularly with the glycosylated formulations (T1307-Glu/FNZ and F127-Glu/FNZ) with a drop in tumor sizes, respect to the control, at the end of the treatments (Figure 4). This evidence concerns the gene FN1 and neoplasm.