In the current systematic review, 3/14 pregnancies complicated with AOSD ended in premature delivery which is comparable to that reported by Mok et al. In a study by Garcia-Fernandez et al., on women with SJIA, 20% had preterm delivery [85], which is in contrast to the current work in which we observed no preterm delivery in SJIA with anti-IL-1 treatment. Here, IL1B is linked to adult-onset Still disease.