SLC5A2 and acute kidney injury: We propose that the different pat-terns of AKI/AKR association in diabetics vs. non diabetics reflect additional factors affecting AKR but not AKI, which may not be related to reversible tubular injury, such as the rapid restoration of volume depletion provoked by osmotic diuresis, withholding RAAS blockers or SGLT2 inhibitors during the acute illness, or the resumption of interrupted medications controlling glucose levels.