In recent decades, few papers have raised attention on the association of atopic disorders (ADs), particularly atopic dermatitis, allergic asthma, and allergic rhinitis, with immuno-inflammatory diseases including SpAs, through the common pathogenetic pathway of the IL-17/IL-23 axis with Th2 disbalance and high immunoglobulin E serum concentrations [6,7,8,9]. The gene discussed is IL17A; the disease is allergic asthma.