According to the literature, in one to two year-old patients with hypoxia and the cyanotic form of TF, the expression of the type Iα procollagen gene is increased fourfold, and the expression of the VEGF gene and glycolytic enzymes is two to five times reduced, compared with the non-cyanotic form of this CHD [69,71]. This evidence concerns the gene VEGFA and coronary artery disorder.