MLKL and cancer: On the other hand, the exposure of the cancer cells to NF or DF brought about a marked increase in the fluorescence signal (Figure 5C and Figure 6C and Supplementary Figure S5), which suggests the intensification of both the MLKL activation and oligomerization, although the dynamics (Figure 5B and Figure 6B) of this process and its nature (Figure 5C and Figure 6C) were strongly dependent on the variant structure and cell type.