This protein can bind to fibrinogen, fibronectin, laminin, type V collagen, and integrins alpha-V/beta-1, hsa-miR-132-3p, and hsa-miR-212-3p, inversely related to CD44, which was previously found upregulated in severe Alzheimer’s disease [46]. This evidence concerns the gene CD44 and early-onset autosomal dominant Alzheimer disease.