This led to the discovery of six patients who met the diagnosis criteria for MM at the time of ≥10% abnormal bone marrow plasma cells (BMPCs) and a serum M-protein concentration >3 g/dL [4], but they did not present with the characteristic CRAB (hypercalcemia, renal failure, anemia, and lytic bone lesions) features of MM [1,4]. Here, MYOM2 is linked to Miyoshi myopathy.