CXCR3 and melanoma: For example, melanoma cells expressing CCR9 are often expected to metastasize in the intestine [45], CCR6 or CXCR4 in lung [46] and liver [47], CCR4 associated with brain metastases [48], whereas cells with high expression of CCR10, CCR7, and CXCR3 populate regional lymph nodes [49].