As observed in our previous study [33], the αSyn_RT-QuIC products generated by OM-MSA (RQ-MSA1 and RQ-MSA2) were considerably more resistant to proteolytic digestion than those generated by OM-PD (RQ-PD1 and RQ-PD2) (Figure 1B). The gene discussed is SNCA; the disease is ocular melanoma.