CD4 and COVID-19: More important, we found some unique VDJ recombination of TRB was shared in both CD4+ T cells and CD8+ T cells of two-week convalescent COVID-19 patients, including TRBV6-5/D2/TRBJ2-7 and TRBV2/D1/TRBJ2-1, suggesting that these T cell clones with the above VDJ recombination were specific for SARS-CoV-2 antigen (Figure 3D,F).