Different experimental evidence, by contrast, supports the hypothesis that mTOR signalling could be a crucial mediator of photoreceptor degeneration in response to nutrient changes in different models of retinitis pigmentosa (RP), including Rd10, Pde6b−/−, Pde6g−/−, Rho−/− and RHO-P23H transgenic mouse models [59,60]. This evidence concerns the gene MTOR and retinitis pigmentosa 1.